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For Immediate Release
Office of the Press Secretary
August 9, 2001

Remarks by the President on Stem Cell Research


The Bush Ranch
Crawford, Texas

8:01 P.M. CDT

     THE PRESIDENT:   Good evening.  I appreciate you giving me a few minutes of your time tonight so I can discuss with you a complex and difficult issue, an issue that is one of the most profound of our time.

     The issue of research involving stem cells derived from human embryos is increasingly the subject of a national debate and dinner table discussions.  The issue is confronted every day in laboratories as scientists ponder the ethical ramifications of their work.  It is agonized over by parents and many couples as they try to have children, or to save children already born.

     The issue is debated within the church, with people of different faiths, even many of the same faith coming to different conclusions.  Many people are finding that the more they know about stem cell research, the less certain they are about the right ethical and moral conclusions.

     My administration must decide whether to allow federal funds, your tax dollars, to be used for scientific research on stem cells derived from human embryos.  A large number of these embryos already exist.  They are the product of a process called in vitro fertilization, which helps so many couples conceive children.  When doctors match sperm and egg to create life outside the womb, they usually produce more embryos than are planted in the mother.  Once a couple successfully has children, or if they are unsuccessful, the additional embryos remain frozen in laboratories.

     Some will not survive during long storage; others are destroyed.  A number have been donated to science and used to create privately funded stem cell lines.  And a few have been implanted in an adoptive mother and born, and are today healthy children.

     Based on preliminary work that has been privately funded, scientists believe further research using stem cells offers great promise that could help improve the lives of those who suffer from many terrible diseases -- from juvenile diabetes to Alzheimer's, from Parkinson's to spinal cord injuries.  And while scientists admit they are not yet certain, they believe stem cells derived from embryos have unique potential.

     You should also know that stem cells can be derived from sources other than embryos -- from adult cells, from umbilical cords that are discarded after babies are born, from human placenta.  And many scientists feel research on these type of stem cells is also promising.  Many patients suffering from a range of diseases are already being helped with treatments developed from adult stem cells.

     However, most scientists, at least today, believe that research on embryonic stem cells offer the most promise because these cells have the potential to develop in all of the tissues in the body.

     Scientists further believe that rapid progress in this research will come only with federal funds.  Federal dollars help attract the best and brightest scientists.  They ensure new discoveries are widely shared at the largest number of research facilities and that the research is directed toward the greatest public good.

     The United States has a long and proud record of leading the world toward advances in science and medicine that improve human life.  And the United States has a long and proud record of upholding the highest standards of ethics as we expand the limits of science and knowledge. Research on embryonic stem cells raises profound ethical questions, because extracting the stem cell destroys the embryo, and thus destroys its potential for life.  Like a snowflake, each of these embryos is unique, with the unique genetic potential of an individual human being.

     As I thought through this issue, I kept returning to two fundamental questions:  First, are these frozen embryos human life, and therefore, something precious to be protected?  And second, if they're going to be destroyed anyway, shouldn't they be used for a greater good, for research that has the potential to save and improve other lives?

     I've asked those questions and others of scientists, scholars, bioethicists, religious leaders, doctors, researchers, members of Congress, my Cabinet, and my friends.  I have read heartfelt letters from many Americans.  I have given this issue a great deal of thought, prayer and considerable reflection.  And I have found widespread disagreement.

     On the first issue, are these embryos human life -- well, one researcher told me he believes this five-day-old cluster of cells is not an embryo, not yet an individual, but a pre-embryo.  He argued that it has the potential for life, but it is not a life because it cannot develop on its own.

     An ethicist dismissed that as a callous attempt at rationalization. Make no mistake, he told me, that cluster of cells is the same way you and I, and all the rest of us, started our lives.  One goes with a heavy heart if we use these, he said, because we are dealing with the seeds of the next generation.

     And to the other crucial question, if these are going to be destroyed anyway, why not use them for good purpose -- I also found different answers.  Many argue these embryos are byproducts of a process that helps create life, and we should allow couples to donate them to science so they can be used for good purpose instead of wasting their potential.  Others will argue there's no such thing as excess life, and the fact that a living being is going to die does not justify experimenting on it or exploiting it as a natural resource.

     At its core, this issue forces us to confront fundamental questions about the beginnings of life and the ends of science.  It lies at a difficult moral intersection, juxtaposing the need to protect life in all its phases with the prospect of saving and improving life in all its stages.

     As the discoveries of modern science create tremendous hope, they also lay vast ethical mine fields.  As the genius of science extends the horizons of what we can do, we increasingly confront complex questions about what we should do.  We have arrived at that brave new world that seemed so distant in 1932, when Aldous Huxley wrote about human beings created in test tubes in what he called a "hatchery."

     In recent weeks, we learned that scientists have created human embryos in test tubes solely to experiment on them.  This is deeply troubling, and a warning sign that should prompt all of us to think through these issues very carefully.

     Embryonic stem cell research is at the leading edge of a series of moral hazards.  The initial stem cell researcher was at first reluctant to begin his research, fearing it might be used for human cloning.  Scientists have already cloned a sheep.  Researchers are telling us the next step could be to clone human beings to create individual designer stem cells, essentially to grow another you, to be available in case you need another heart or lung or liver.

     I strongly oppose human cloning, as do most Americans.  We recoil at the idea of growing human beings for spare body parts, or creating life for our convenience.  And while we must devote enormous energy to conquering disease, it is equally important that we pay attention to the moral concerns raised by the new frontier of human embryo stem cell research. Even the most noble ends do not justify any means.

     My position on these issues is shaped by deeply held beliefs.  I'm a strong supporter of science and technology, and believe they have the potential for incredible good -- to improve lives, to save life, to conquer disease.  Research offers hope that millions of our loved ones may be cured of a disease and rid of their suffering.  I have friends whose children suffer from juvenile diabetes.  Nancy Reagan has written me about President Reagan's struggle with Alzheimer's.  My own family has confronted the tragedy of childhood leukemia.  And, like all Americans, I have great hope for cures.

     I also believe human life is a sacred gift from our Creator.  I worry about a culture that devalues life, and believe as your President I have an important obligation to foster and encourage respect for life in America and throughout the world.  And while we're all hopeful about the potential of this research, no one can be certain that the science will live up to the hope it has generated.

     Eight years ago, scientists believed fetal tissue research offered great hope for cures and treatments -- yet, the progress to date has not lived up to its initial expectations.  Embryonic stem cell research offers both great promise and great peril.  So I have decided we must proceed with great care.

     As a result of private research, more than 60 genetically diverse stem cell lines already exist.  They were created from embryos that have already been destroyed, and they have the ability to regenerate themselves indefinitely, creating ongoing opportunities for research.  I have concluded that we should allow federal funds to be used for research on these existing stem cell lines, where the life and death decision has already been made.

     Leading scientists tell me research on these 60 lines has great promise that could lead to breakthrough therapies and cures.  This allows us to explore the promise and potential of stem cell research without crossing a fundamental moral line, by providing taxpayer funding that would sanction or encourage further destruction of human embryos that have at least the potential for life.

     I also believe that great scientific progress can be made through aggressive federal funding of research on umbilical cord placenta, adult and animal stem cells which do not involve the same moral dilemma.  This year, your government will spend $250 million on this important research.

     I will also name a President's council to monitor stem cell research, to recommend appropriate guidelines and regulations, and to consider all of the medical and ethical ramifications of biomedical innovation.  This council will consist of leading scientists, doctors, ethicists, lawyers, theologians and others, and will be chaired by Dr. Leon Kass, a leading biomedical ethicist from the University of Chicago.

     This council will keep us apprised of new developments and give our nation a forum to continue to discuss and evaluate these important issues. As we go forward, I hope we will always be guided by both intellect and heart, by both our capabilities and our conscience.

     I have made this decision with great care, and I pray it is the right one.

     Thank you for listening.  Good night, and God bless America.

     END  8:12 P.M. CDT

http://www.whitehouse.gov/ news/releases/ 2001/08 /print/20010809-2.html

Press Release : Juvenile Diabetes Research Foundation International

Washington, D.C., April 28, 2004- Juvenile Diabetes Research Foundation (JDRF) International Chairman Mary Tyler Moore today joined U.S. Representatives Michael Castle (R-DE), Randy “Duke” Cunningham (R-CA), Diana DeGette (D-CO), and Calvin Dooley (D-CA) on Capitol Hill to release a letter co-signed by more than 200 Members of Congress urging President Bush to expand the three year old policy on federal funding of stem cell research.
press release

Contact: Peter Cleary (pcleary@jdrf.org), JDRF National Director of Media Relations
Phone: (212) 479-7553 Office and (917) 698-8779 Cell

Juvenile Diabetes Research Foundation International Chairman Mary Tyler Moore Joins More than 200 Members of Congress in Urging Expansion of Bush Administration Embryonic Stem Cell Policy
New Poll Shows Two-Thirds of All Americans Support Expansion of Federal Policy

Washington, D.C., April 28, 2004-Juvenile Diabetes Research Foundation (JDRF) International Chairman Mary Tyler Moore today joined U.S. Representatives Michael Castle (R-DE), Randy “Duke” Cunningham (R-CA), Diana DeGette (D-CO), and Calvin Dooley (D-CA) on Capitol Hill to release a letter co-signed by more than 200 Members of Congress urging President Bush to expand the three year old policy on federal funding of stem cell research.

“We will not be able to deliver the cures promised by stem cell research unless we expand current federal policy,” said JDRF International Chairman Mary Tyler Moore. “I know this is a difficult issue for many. And none of us should minimize how hard it is or how important it is for us, together, to come to terms with the balance of pros and cons. We are, after all, dealing with life in its most vulnerable stages - at its nascence and when it is challenged by deadly illness.  Like President Bush, I am pro-life.  But unlike the President, I feel we show special reverence for the potential life that resides in excess IVF embryos by allowing them to save lives in the future rather than watch them be discarded as medical waste without that option.”

“Because of the great potential of stem cell research, allowing couples to donate un-used fertilized eggs is much like the life-giving choice a mother whose child has died tragically in an automobile accident makes when donating his organs to save another mother’s child,” added Mary Tyler Moore. “It is the true pinnacle of charity to give so totally, so freely, of ones self, to give life to another. And Federal support for stem cell research is an extension of this affirmation of life and is the best way to insure it is undertaken with the highest of ethical standards.”

“On August 9, 2001, I appeared on national television following President Bush’s first televised address to the nation, when he announced his decision to allow stem cell funding,” continued Mary Tyler Moore. “Even though I preferred a more expansive policy, I supported the President at that time.  I knew that he gave careful thought in developing his position, and that every day that went by without focusing on research was another day lost in our fight to cure a wide range of diseases. But what we face today is the unfortunate fact that we can’t achieve our mutual goal of using stem cell research to cure devastating diseases, sooner rather than later. I don’t believe this is the outcome that President Bush sought, and it is certainly one which is painfully unacceptable for the millions of children, the millions of mothers and fathers, the millions of doctors and lawyers and teachers and nurses and homemakers and mechanics and plumbers and electricians - and actors - who look to stem cell science to improve the quality and length of their lives.”

Embryonic stem cells are special cells that can develop into every type of cell in the human body.  The stem cells are created from frozen embryos in fertility clinics, donated by couples that no longer want or need the embryo because they have finished with their fertility treatments.  If not donated for research, the frozen embryos would otherwise be discarded.  In August of 2001, the Bush Administration announced that federal funding would be available for limited embryonic stem cell research, on just a few stem cell lines that were developed before that date.  Researchers are now saying that this policy is hampering the advancement of science, slowing the search for cures to a wide range of diseases, and that President Bush should expand it to allow access to additional stem cell lines.

Adding to the momentum of today’s announcement by Members of Congress was the release on Monday of a national survey by the Civil Society Institute (www.resultsforAmerica.org) that showed stem cell research is supported by a strong majority of voters, especially independents. The survey, conducted by Peter D. Hart Research Associates, showed that two out of three voters in the18 states where the survey was conducted support expanding the Bush administrations limits on federal government funding for embryonic stem cell research.

 “Stem cell research is something that Americans want to see advanced in an ethical and expeditious manner, using fertilized eggs from fertility clinics destined to be discarded for research,” said Civil Society Institute President Pam Solo. “The vast majority of Americans, regardless of religious affiliation or political party, understand the need for moving ahead with stem cell research.”

With stem cell research partnerships in the United Kingdom, Sweden, France, Australia, Canada and Singapore, as well as the United States, JDRF is a global leader in direct support of human stem cell research.  JDRF’s also supports the International Society for Stem Cell Research (www.isscr.org) as a critical means for the world’s top stem cell scientists to communicate and build collaborations focused on developing stem cell therapies.

JDRF (www.jdrf.org) was founded in 1970 by the parents of children with juvenile diabetes - a disease that strikes children suddenly, makes them insulin dependent for life, and carries the constant threat of devastating complications.  Since inception, JDRF has provided more than $680 million to diabetes research worldwide.  More than 80 percent of JDRF’ expenditures directly support research and education about research.  JDRF’s mission is constant:  to find a cure for diabetes and its complications through the support of research.

http://www.jdrf.org/ index.cfm?fuseaction= home.viewPage&page_id= 2D2F4E1C-2A5E-7B6E- 10B3A5486C79F80B


Dear Mr. President:

We write to urge you to expand the current federal policy concerning embryonic stem cell research.

As you know, embryonic stem cells have the potential to be used to treat and better understand deadly and disabling diseases that affect more than 100 million Americans, such as cancer, heart disease, diabetes, Parkinson's, Alzheimer's, multiple sclerosis, spinal cord injury, and many others.

Embryonic stem cells are derived from in vitro fertilized (IVF) embryos that are developed in excess of those needed for the process to allow infertile couples to have children. The IVF process results in more embryos than are needed by the couple. There are estimated to be more than 400,000 IVF embryos, which are currently frozen and will likely be destroyed if not donated, with informed consent of the couple, for research.

We very much appreciate your words of support for the enormous potential of this research, and we know that you intended your policy to help promote this research to its fullest. As you know, the Administration's policy limits federal funding only to embryonic stem cells that were derived by August 9, 2001, the date of the policy announcement.

However, scientists have told us that since the policy went into effect more than two years ago, we have learned much more about why the embryonic stem cell lines eligible for federal funding will not be suitable to effectively promote this research. We therefore feel it is essential to relax the restrictions in the current policy for this research to be fully explored.

Among the current challenges with the current policy are the following:

While it originally appeared that 78 embryonic stem cell lines would be available for research under the federal policy, now, more than two years after August 9, 2001, only 15 are available to researchers.

· All available stem cell lines are contaminated with mouse feeder cells, making their therapeutic use for humans uncertain.

· Scientists are reporting that it is increasingly difficult to attract new scientists to this area of research because of concerns that funding restrictions will keep this research from being successful.

· This promising field of research is moving overseas. We have already seen researchers move to countries like the United Kingdom, which have more supportive policies. In addition, leadership in this area of research has shifted to the United Kingdom, which sees this scientific area as a cornerstone of its biotech industry and which is leading the International Stem Cell Forum, made up of scientific agencies from nearly a dozen countries.

Mr. President, we know that you have been a strong supporter of medical research and share our commitment to curing disease and alleviating human suffering. We would very much like to work with you to modify the current embryonic stem cell policy so that it provides this area of research the greatest opportunity to lead to the treatments and cures we all are hoping for.

Sincerely,

Members of Congress

[This letter is reproduced at the website of Congressman Christopher Shays
http://www.house.gov/ shays/news/2004/ april/aprstem.htm and in PDF form at the International Society for Stem Cell Research website: http://www.isscr.org/ press_releases/Stemcell.pdf]



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