Diabetes Monitor - Information, education, and support for people with diabetes

Would Metformin Prevent Insulin Resistance And Help Me Lose Weight

Publication Date: 11/19/2005

 


Remember that the information presented here is not intended to replace the care of your own doctor. Before making any changes in the management of your own illness, you should consult your physician or other qualified medical professionals.

 


 

Question

I am 52 years old and have had hypothyroidism for the last two years which is controlled with medication. However, I have put on excessive weight in the last year (10 kg [22.2 pounds]) and my metabolic rate is very slow. Hence, I am not responding to various diets. I have not been successful, and my main problem is that I feel excessively sleepy and fatigued all the time.Could this be a reaction with the thyroid drug?

My doctor put me on Riomet [metformin] to prevent insulin resistance and to help me lose weight. Would this work?

Answer

Metformin is approved for use in type 2 diabetes. It is also frequently used off-label for PCOS and sometimes in pre-diabetes. However, I am unaware of any recommendation for use in patients with thyroid disease and obesity.

I'd suggest you ask your physician for clarification of why he/she thought that metformin would be of help. Since metformin does have significant side effects, I'd be hesitant to use it off-label unless there are scientific studies that support its use — you might ask for the titles of such articles and look them up yourself at PubMed.


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