is this really diabetes?
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Remember that the information presented here is not intended to replace the care of your own doctor. Before making any changes in the management of your own illness, you should consult your physician or other qualified medical professionals.


Question

I am 39 and was recently diagnosed with type 2 diabetes, with an HbA1c of 5.8. I do have a family history of heart disease and diabetes, and I did have gestational diabetes with my second child, and have been on 500 mg/day of Glucophage XR for about one year to combat Impaired Glucose Tolerance. But isn't that number well in the normal range? I thought anything below 6 was a normal A1c result.

I exercise, eat right, and keep my weight in check — my BMI is well within the normal range. I want to have a face to face with my doctor but want to be prepared with the right questions about my diagnosis. Is this really diabetes?

Answer

The diagnosis of diabetes is not based on HbA1c values. The diagnosis is based on serum glucose levels, by venipuncture:

A confirmed fasting serum glucose level of > 125 mg/dL defines diabetes; as does:

  • A random serum level >200 if there are classic symptoms such as increased thirst or urination; as does
  • A level > 200 at the 2 hour mark during a properly performed glucose tolerance test.
There are different techniques and assays to assess glycohemoglobin and things other than glucose can influence it. I assume that you do have glucose intolerance and the Glucophage is not an unreasonable choice. But if your glucose levels are good, and you are exercising and watching your diet, then you can talk to your physician about consideration of a trial without it.

But if you do indeed have type 2 diabetes, you would do well to stay on your current plan as you are well controlled, at least based on the HbA1c value you provide.

ids     

Also, your A1c might be in "normal" range because you have been taking Glucophage XR for a year already. As Dr. Schwartz indicates, to diagnose type 2 diabetes, three tests can be done:

  1. a Fasting Plasma Glucose (FPG), (no food for 8 hours), performed on two different days.
  2. a random blood glucose; drawings performed on two different days (time of day doesn't matter).
  3. an Oral Glucose Tolerance Test.

slb     

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31Oct2004  
 

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