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is this dose of medications overkill?
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Remember that the information presented here is not intended to replace the care of your own doctor. Before making any changes in the management of your own illness, you should consult your physician or other qualified medical professionals.


Question

I had a test for what I guess was three month span of blood sugar levels and my average was 268 mg/dL along with a fasting blood sugar of 353 mg/dL. I've not been following my diet, and I eat anything. The doctor at the VA had me on 10 mg of glipizide twice per day, and because of the high numbers, she's putting me on 1000 mg of metformin once per day. She also told me to increase this to twice per day for two weeks. Has anyone ever had this large dosage to start out with? Is it overkill?

Answer

1000 mg of metformin per day is an entirely reasonable dose. The biggest concern about starting with 1000 mg rather than 500 mg is the fact that the gut side effects of metformin are somewhat dose-dependent. So, if you get problems, cut the dose back to 500 mg and notify your physician.

On a somewhat different note, it's impossible for any pills to control your diabetes if you continue to ignore your meal plan. You should talk with the diabetes dietitian and sort out what changes you could make to help control your diabetes.

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