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does this mean every person with diabetes cannot take metformin?
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Question

I'm confused with your explanation concerning who should not take metformin. It said that people who have liver problems should not, but I know that every person with diabetes has a liver problem. (It cannot produce enough insulin to burn the glucose.) So, this means every person with diabetes cannot take metformin. I hope you can explain it.

Answer

First of all, for clarification, insulin is produced by the pancreas, not the liver.

Not every person with diabetes has a liver problem. The type of liver problem that some people with diabetes have is called "fatty liver" (see nonalcoholic steatohepatitis for more information).

However, I agree that the label for metformin is unclear when it says people who "have liver problems" should not take this medication. The type of liver problem that is of concern with use of metformin is fortunately relatively rare. Most physicians would assume that people with such problems would have jaundice or elevated levels of bilirubin, and elevated levels of enzymes called transaminases.

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