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It is estimated that over six million reproductive-age women in the United States have Polycystic Ovary Syndrome (PCOS) and many do not know they have it. The full and far reaching implications for health and well-being are often underappreciated. Public information and awareness about the symptoms and the serious nature of this disorder are crucial to identifying women in need of treatment.


HOW DO I KNOW IF I HAVE PCOS?

Polycystic Ovary Syndrome is an extremely common disorder which is characterized by abnormal regulation of ovarian hormones and systemic metabolic abnormalities. It may present as:
  • Irregular or infrequent menstrual bleeding and/or infertility
  • Evidence of increased androgens which cause increased facial/body hair growth or acne
  • Multiple small cysts in the ovary as seen on an ultrasound scan
When one abnormality is found, others should be sought. PCOS is often considered a purely gynecological disorder since many PCOS symptoms involve a woman's reproductive system. It is, however, a systemic disorder involving hormones, sugar metabolism, lipids and blood vessels.

In addition to the above, there are a number of other clues that may increase the suspicion of PCOS:

  • Problems maintaining normal weight
  • Infertility/recurrent pregnancy loss
  • Family members with PCOS
  • Family history of diabetes or heart disease
  • High blood sugar
  • Darkened patches of skin on the neck, groin, under arms, or in skin folds
  • Frontal balding or scalp hair loss
  • Skin tags
  • Elevated cholesterol, low HDL, or high triglycerides
PCOS may manifest itself differently in each woman. Some with PCOS may have relatively regular periods; some are thin and some have no obvious skin problems; most are at risk for serious long-term health problems if not appropriately evaluated.

WHAT TREATMENT OPTIONS ARE AVAILABLE?

While PCOS cannot yet be cured, it can be controlled. Specifi c therapies are available for each of the many symptoms of PCOS. For those who are overweight, menstrual cycle regularity and ovulation may return with even modest reductions in weight. Regular exercise and tobacco avoidance has been conclusively shown to lessen the risk of cardiovascular disease. Often lifestyle modifi cation is not enough. There are a number of medications and therapies available. By early intervention, the long-term consequences of PCOS can be postponed and possibly prevented.

WHAT ARE THE POSSIBLE LONG-TERM HEALTH CONSEQUENCES OF PCOS?

Heart & Cardiovascular Disease

Women with PCOS are at increased risk for heart attack and strokes. All women with PCOS should have periodic cholesterol testing and blood pressure monitoring.*

Type 2 Diabetes

The risk of type 2 diabetes is increased in all women with PCOS, particularly those who are obese have had gestational diabetes or a family history of diabetes. AACE recommends diabetes screening for women with PCOS beginning at age 30, with repeated yearly testings for those with negative results. In some people, a glucose challenge test may be recommended.

Endometrial Cancer

The risk of endometrial (uterine) cancer is increased with obesity, infertility, heavy and infrequent periods. Heavy bleeding, lack of periods, or changes in bleeding pattern should be discussed with your physician.

HOW CAN I FIND HELP?

The AACE website offers a "Find an Endocrinologist" service where you can search for an endocrinologist within a certain radius of your home, school or office. For more information, visit www.aace.com. Also visit AACE's patient-focused website, www.powerofprevention.com, and fill out your own personalized health report to help you monitor your blood sugar, cholesterol and blood pressure.


Reproduced with permission from the American Association of Clinical Endocrinologists
April 2001
http://www.aace.com/pub/pcos2004/pcosbochure.pdf

Also see

AACE Public Awareness Campaign about PCOS
Ovarian Cysts
polycystic ovary syndrome



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