Diabetes Monitor - Diabetes Monitor - Medications To Lower High Blood Pressure

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Publication Date: 1/6/2010

Category	Brand Name	Generic Name	Manufacturer	Minimum Daily Dose	Maximum Daily Dose	Special Considerations
Angiotensin- converting enzyme (ACE) inhibitors	Mavik	trandolapril	Abbot	1	8	May cause cough.May increase potassium concentrations.Do not use potassium or salt substitutes without consulting physician.Do not use if pregnant or if trying to conceive.Caution if creatinine >1.5.
	Altace	ramipril	Monarch	1.25	20
	Capoten	captopril	Apothecon	25	450
		captopril	generic�	25	450
	Univasc	moexipril	Schwarz	7.5	60
	Monopril	fosinopril	Bristol-MyersSquibb	10	80
	Lotensin	benazepril	Novartis	5	20
	Prinivil	lisinopril	Merck	2.5	80
	Zestril	lisinopril	AstraZeneca	2.5	80
		lisinopril	generic�	2.5	80
	Vasotec	enalapril	Merck	2.5	40
		enalapril	generic�	2.5	40
	Accupril	quinapril	Pfizer	5	80
	Aceon	perindopril	Solvay	4	16
Angiotensin II receptor blockers	Cozaar	losartan	Merck	25	100	May cause dizziness and upset stomach. Do not use potassium or salt substitutes without consulting physician. Do not use if pregnant or if trying to conceive. Caution if creatinine >1.5.
	Benicar	olmesartan	Sankyo	20	40
	Diovan	valsartan	Novartis	80	320
	Avapro	irbesartan	Bristol-Myers Squibb	150	300
	Atacand	candesartan	AstraZeneca	15	32
	Micardis	telmisartan	Boehringer-Ingelheim	20	80
	Teveten	eprosartan	Biovail	400	800
Calcium channel blockers	Sular	nisoldipine	AstraZeneca	20	60	May cause constipation, dizziness, upset stomach, and flushing.Call physician for shortness of breath, unusual heartbeat, or swelling of feet or hands.
	Adalat CC*	nifedipine	Bayer	30	120
	Procardia	nifedipine	Pfizer	30	120
	Procardia XL*	nifedipine	Pfizer	30	120
		nifedipine	generic�	30	120
	Cardene	nicardipine	Roche	60	120
	Cardene SR*	nicardipine	Roche	60	120
	DynaCirc	isradipine	Reliant	2.5	20
	DynaCirc CR*	isradipine	Reliant	2.5	20
	Plendil	felodipine	AstraZeneca	5	20
	Cardizem	diltiazem	Biovail	120	360
	Cardizem CD*	diltiazem	Biovail	120	360
		diltiazem	generic�	120	360
	Dilacor XR*	diltiazem	Watson	180	540
	Tiazac	diltiazem	Forest	120	540
	Calan	verapamil	Searle	120	480
	Calan SR*	verapamil	Searle	120	480
		verapamil	generic�	120	480
	Isoptin	verapamil	Abbott	120	480
	Isoptin SR*	verapamil	Abbott	120	480
	Verelan	verapamil	Schwarz	120	480
	Verelan PM*	verapamil	Schwarz	100	400
	Covera HS*	verapamil	Searle	180	480
	Norvasc	amlodipine	Pfizer	5	10
Thiazides and related diuretics	Diuril	chlorothiazide	Merck	500	2,000	May increase blood glucose concentrations.Take in morning to minimize diuretic effect at night.May cause low potassium.Need blood test to monitor level.
		chlorothiazide	generic�	500	2,000
	HydroDIURIL	hydrochlorothiazide	Merck	15	50
	Microzide	hydrochlorothiazide	Watson	12.5	200
		hydrochlorothiazide	generic�	12.5	200
	Enduron	methyclothiazide	Abbott	2.5	10
	Zaroxolyn	metolazone	Fisons	2.5	10
	Hygroton	chlorthalidone	Aventis	2.5	100
	Lozol	indapamide	Aventis	1.25	5
Loop diuretics	Lasix	furosemide	Aventis	80	80	May cause low potassium. Need blood test to monitor level. May cause photosensitivity: sunscreen recommended.
		furosemide	generic�	80	80
	Bumex	bumetanide	Roche	0.5	10
		bumetanide	generic�	0.5	10
	Demadex	torsemide	Roche	5	20
Potassium-sparing diuretics	Aldactone	spironolactone	Searle	50	400	Do not use potassium or salt substitutes without consulting physician.
		spironolactone	generic�	50	400
	Dyrenium	triamterene	GlaxoSmithKline	50	300
	Midamor	amiloride	Merck	5	20
		amiloride	generic�	5	20
Carbonic anhydrase inhibitors	Diamox	acetazolamide	Wyeth-Ayerst	250	1,000	May take with food if medicine upsets stomach.May cause hand/foot tingling that can be confused with neuropathy.
Carbonic anhydrase inhibitors		acetazolamide	generic�	250	1,000
ß-blockers	Tenormin	atenolol	AstraZeneca	25	100	May mask signs of low blood glucose levels.May alter blood glucose.Call physician for slow heart rate (<60), confusion, or swelling of feet or legs.Can cause claudication.
		atenolol	generic�	25	100
	Kerlone	betaxolol	Searle	5	40
		betaxolol	generic�	5	40
	Levatol	penbutolol	Schwarz	10	40
	Zebeta	bisoprolol	Lederle	2.5	20
	Lopressor	metoprolol	Novartis	25	450
		metoprolol	generic�	25	450
	Toprol XL*	metoprolol	AstraZeneca	50	400
	Corgard	nadolol	Bristol-MyersSquibb	40	320
		nadolol	generic�	40	320
	Inderal	propranolol	Wyeth-Ayerst	40	640
	Inderal LA*	propranolol	Wyeth-Ayerst	40	640
			generic�	40	640
α-blockers	Minipress	prazosin propranolol	Pfizer	1	20	To prevent dizziness, avoid standing up suddenly, especially with the first few doses.
		prazosin	generic�	2	40
	Hytrin	terazosin	Abbott	1	40
		terazosin	generic�	1	40
	Cardura	doxazosin	Roerig	1	16
		doxazosin	generic�	1	16
Combined α-and ß-blockers	Trandate	labetalol	Faro	100	2,400	May mask signs of low blood glucose levels.Take with food to avoid stomach upset.
	Normodyne	labetalol	Key	100	2,400
		labetalol	generic�	100	2,400
	Coreg	carvedilol	GlaxoSmithKline	6.25	50
Direct vasodilators	Apresoline	hydralazine	Novartis	40	300	May cause headaches, fluid retention, or fast heart rate.
Central a-agonists	Catapres	clonidine	Boehringer-Ingelheim	0.1	2.4	Do not discontinue drug suddenly without consulting physician.
		clonidine	generic�	0.1	2.4
	Catapres TTS*(patch)	clonidine	Boehringer-Ingelheim	0.1	0.6
	Aldomet	methyldopa	Merck	250	3,000
		methyldopa	generic�	250	3,000
*Agents in a class of medicines share mechanisms of action, require similar precautions and generally have similar side effects. CC = extended release XL = extended release LA = long acting †generic = generic drug manufacturers SR = sustained release CR = controlled release CD = extended release XR = extended releasePM = extended release, controlled onset HS = extended release, controlled onset �generic = generic drug manufacturers Adapted from Kings Publishing, Inc. For subscription information call 1-800-488-8468. TTS = transdermal therapeutic system �generic = generic drug manufacturers

For all anti-hypertensives:

Ask pharmacist before using OTC products.

Monitor blood pressure regularly.

To prevent dizziness, advise patient to stand up slowly. If dizziness persists, refer to health care provider.

Information about high blood pressure can be found at the following Web sites:

Health care professionals: www.nhlbi.nih.gov/health/prof/heart/index.htm
Information for people with diabetes: www.nhlbi.nih.gov/hbp
Drugs used to treat high blood pressure: www.nhlbi.nih.gov/guidelines/hypertension/express.pdf

Centers for Disease Control and Prevention. Working Together to Manage Diabetes: Diabetes Medications Supplement. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, 2004.

From the National Diabetes Education Program
Working Together to Manage Diabetes: A Guide for Pharmacists, Podiatrists, Optometrists, and Dental Professionals
NDEP-54-S
http://www.ndep.nih.gov/diabetes/WTMD/diabets_suppl_4.htm

Also see

Other webpages about high blood pressure